To maximize the test dimensions while increasingrams the power in order to place SNP relationships, i outlined all of our prie sex spouse
Like a measure does not get the brand new multifaceted fullness and complexity from people sexual orientation. To understand more about the effects in the simplification, we pursued hereditary analyses all over different factors regarding sexual positioning and you may behavior.
I centered that fundamental genetic structures is extremely advanced; there is certainly no genetic determinant (both called new “gay gene” from the mass media)
First, within participants reporting same-sex sexual behavior, we performed a GWAS on the proportion of same-sex partners to total partners, with a higher value indicating a higher proportion of same-sex partners (14). In the UK Biobank, this is measured directly from participants’ reported number of same-sex and all partners, whereas in 23andMe, we used participants’ raw responses to the item “With whom have you had sex?”, which in individuals reporting same-sex sexual behavior could be “other sex mostly,” “other sex slightly,” “equal,” “same sex slightly,” “same sex mostly,” or “same sex only.” The UK Biobank and 23andMe variables were heritable (table S20A) and genetically correlated with each other (rg = 0.52 and 95% CIs, ? 0.16 to 1.20 for females; rg = 0.73 and 95% CIs, 0.18 to 1.27 for males) ( Fig. 5A and table S20C), so we used MTAG to meta-analyze across the two studies for subsequent analyses. Read more →